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quinupristin/dalfopristin will increase the stage or impact of bosentan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.quinupristin/dalfopristin will improve the amount or impact of lumateperone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Cut down lumate